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Qilu Pharmaceutical a2a ar antagonists
A2a Ar Antagonists, supplied by Qilu Pharmaceutical, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/a2a+ar+antagonists/a2a+ar+antagonists/pm40494262-48-6-0
Average 90 stars, based on 1 article reviews
a2a ar antagonists - by Bioz Stars, 2026-11
90/100 stars

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Article Title: Design, synthesis, and biological evaluation of A 2A adenosine receptor antagonists containing pyrrolo[2,3-d]pyrimidin-2-amine skeleton.
Article Snippet: A series of novel A2A adenosine receptor (AR) antagonists containing a pyrrolo[2,3-d]pyrimidin-2-amine skeleton were developed through a bioisosterism strategy based on human A2A AR structures.. The synthesis of all targeted compounds was accomplished, and their inhibitory effectiveness against the A2A AR was assessed using cAMP assays.. Notably, compounds 12a and 18e demonstrated superior inhibitory effects compared to the control compounds AB928 and ZM241385.



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